Although´measurement of cerebral blood flow by raidoactive isotope became popular, there is still no report of study on the cerebral blood flow in Korea.
Auther studied the regional blood flow in 28 normal Korean adults and 76 patients including 14 cases of essential hypertension, 11 cases of heart diseases (coronary artery disease, valvular diseases and AN block), 14 cases-of brain diseases (cerebral thrombosis and cerebral insufficiency), 22 cases of head trauma and 15 cases of miscellaneous medical diseases. The regional cerebral blood flow was measured by intravenous injection of ^(99m)Tc-DTPA 15~20mCi and by taking serial cerebral angiograms with CGR Gamma Tome 7000 and was analyized by Computer Imac 7310.
The results were as follows;
1. The average regional cerebral blood flow of normal Korean adult was 50.0±5.89ml/100/g/min. with range of 41-60ml/100g/min.
2. In most cases of essential hypertension, the regional cerebral blood flow was within normal limit except rare case which was considered to have impaired autoregulation of cerebral blood low.
3. In patients with myocardial infarction, valvular heart diseases with congestive heart failure and complete A-V block, there was markedly reduced cerebral blood flow. The. reduced crebral blood flow increased after the improvement of congestive heart failure and after the implantation of pacemaker.
4. In patients with cerebral thrombosis with infarction and cerebral insufficiency with syptoms of dizziness, headache or blurring vision, the cerebral blood flow was considerably reduced. However in acute encephalits the cerebral blood flow was increased. The measurement of cerebral blood flow by radioactive isotope method is considered to accurate, easy and useful clinical test to evaluate brain disease and function.
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